PABPC4 BROADLY INHIBITS CORONAVIRUS REPLICATION BY DEGRADING NUCLEOCAPSID PROTEIN THROUGH SELECTIVE AUTOPHAGY

ABSTRACT Emerging coronaviruses (CoVs) can cause severe diseases in humans and animals, and, as of yet, none of the currently available broad-spectrum drugs or vaccines can effectively control these diseases.Host antiviral proteins play an important role in inhibiting viral proliferation.One of the isoforms of cytoplasmic poly(A)-binding protein (P

In the traditional marriage there is an unequal power Toy Gift Set relationship between the spouses.The husband is in the dominant role and his wife is subordinate to him.Presumably this state of affairs would be justified if a relevant universal difference could be found between men and women such as would entail male domination.Can such a differe